Manager CMC Materials Management

Job description

Headquarters: Mumbai, Maharashtra, India URL: http://www.praxismedicines.com Location: India - Remote The Opportunity At Praxis, every material movement matters. We are seeking a proactive, results-driven Manager, CMC Materials Management to own domestic and international logistics supporting our research, development, and manufacturing programs. This role ensures critical materials reach the right destination, on time and in the required condition, while maintaining compliance, inventory visibility, and cost efficiency across our global supplier and CDMO network. The ideal candidate anticipates challenges, solves problems with urgency, and takes ownership from planning through delivery. Success requires strong execution, attention to detail, and a commitment to advancing life-altering medicines for patients. Primary Responsibilities Own end-to-end materials logistics: Plan and execute domestic and international shipments supporting CMC development, technology transfers, and manufacturing. Coordinate suppliers, carriers, freight forwarders, customs brokers, and internal teams to ensure timely, reliable delivery. Ensure shipment integrity and compliance: Manage temperature-controlled shipments, packaging, monitoring, and material-specific handling requirements. Partner with Quality and Regulatory to ensure compliance with applicable procedures and promptly escalate excursions or deviations for assessment and disposition. Drive accurate documentation and execution: Oversee shipping requests, including E-Transparency submissions, commercial invoices, packing lists, customs documentation, and Material Transfer Requests. Ensure complete, accurate, and timely records in the Quality Management System (QMS). Maintain inventory visibility: Track and reconcile material inventories at CDMOs and external partners, monitoring stock levels, expiry dates, and availability. Coordinate replenishment and transfers to prevent disruptions to development and manufacturing schedules. Manage logistics partners: Partner with Quality and Procurement to select, onboard, and oversee service providers. Support negotiations, establish performance expectations, and hold partners accountable for delivery, quality, responsiveness, and cost. Anticipate and resolve risks: Proactively identify transportation, customs, storage, and supply continuity risks. Develop contingency plans, resolve disruptions with urgency, and communicate clearly with stakeholders through resolution. Improve operational performance: Maintain accurate shipment and inventory records in SharePoint, Excel, and other systems. Track delivery performance, temperature excursions, inventory accuracy, and freight costs. Use data and cross-functional collaboration to simplify processes, improve reliability, and reduce avoidable costs. Qualifications and Key Success Factors Bachelor's degree in Supply Chain, Logistics, Life Sciences, Engineering, or related field, or equivalent experience. Typically 5–8 years of experience in logistics, materials management, or supply chain operations, preferably in biotechnology, pharmaceuticals, or a regulated environment. Experience managing international shipments, customs documentation, freight forwarding, and temperature-controlled logistics. Working knowledge of GxP requirements, quality systems, and pharmaceutical material handling and documentation. Experience coordinating inventory and material movements across CDMOs, suppliers, or external manufacturing partners. Proficiency with Excel, SharePoint, and logistics or inventory management systems; familiarity with E-Transparency, QMS, or ERP systems is a plus. Strong organizational skills, sound judgment, and the ability to manage competing priorities across global teams and partners. Ownership: Takes initiative, follows through, and drives issues to resolution without waiting for direction. Collaboration: Builds trust through clear communication, transparency, and accountability across functi